Protein name:
Mucin-2 (MUC-2) ;
Alternative:
Intestinal mucin-2 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Homotrimer; disulfide-linked. Dimerizes in the endoplasmic reticulum via its C-terminal region and polymerizes via its N-terminal region by disulfide-linked trimerization. Interacts with FCGBP (By similarity). Interacts with AGR2; disulfide-linked.
Function:
Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.
Subcellular Location:
Secreted
In the intestine, secreted into the inner and outer mucus layers.
Protein Attributes:
50:
MGLPLARLVA | VCLVLALAKG | LELQKEARSR | NHVCSTWGDF | HYKTFDGDVF |
100:
RFPGLCDYNF | ASDCRDSYKE | FAVHLKRGLD | KAGGHSSIES | VLITIKDDTI |
150:
YLTHKLAVVN | GAMVSTPHYS | SGLLIEKNDA | YTKVYSRAGL | SLMWNREDAL |
200:
MVELDGRFQN | HTCGLCGDFN | GMQANNEFLS | DGIRFSAIEF | GNMQKINKPE |
250:
VVCEDPEEVQ | EPESCSEHRA | ECERLLTSTA | FEDCQARVPV | ELYVLACMHD |
300:
RCQCPQGGAC | ECSTLAEFSR | QCSHAGGRPE | NWRTASLCPK | KCPGNMVYLE |
350:
SGSPWLDTCS | HLEVSSLCEE | HYMDGCFCPE | GTVYDDITGS | GCIPVSQCHC |
400:
KLHGHLYMPG | QEITNDCEQC | VCNAGRWMCK | DLPCPETCAL | EGGSHITTFD |
450:
GKKFTFHGDC | YYVLTKTKYN | DSYALLGELA | SCGSTDKQTC | LKTVVLLTDN |
500:
KKNVVAFKSG | GSVLLNEMEV | SLPHVAASFS | IFKPSSYHIV | VNTMFGLRLQ |
550:
IQLVPVMQLF | VTLDQSAQGQ | VQGLCGNFNG | LESDDFMTSG | GMVEATGAGF |
600:
ANTWKAQSSC | HDKLDWLDDP | CPLNIESANY | AEHWCSLLKR | SETPFARCHL |
650:
AVDPTEYYKR | CKYDTCNCQN | NEDCMCAALS | SYARACAAKG | VMLWGWRESV |
700:
CNKDVHACPS | SQIFMYNLTT | CQQTCRSISE | GDTHCLKGFA | PVEGCGCPDH |
750:
TFMDEKGRCV | PLSKCSCYHH | GLYLEAGDVI | LRQEERCICR | NGRLQCTQVK |
800:
LIGHTCLSPQ | ILVDCNNLTA | LAIREPRPTS | CQTLVARYYH | TECISGCVCP |
850:
DGLLDNGRGG | CVVEDECPCI | HNKQFYDSGK | SIKLDCNNTC | TCQKGRWECT |
900:
RYACHSTCSI | YGSGHYITFD | GKHYDFDGHC | SYVAVQDYCG | QNSTGSFSII |
950:
TENVPCGTTG | VTCSKAIKIF | IGGTELKLVD | KHRVVKQLEE | GHHVPFITRE |
1000:
VGLYLVVEVS | SGIIVIWDKK | TTIFIKLDPS | YKGNVCGLCG | NFDDQTKNDF |
1050:
TTRDHMVVAS | ELDFGNSWKE | ASTCPDVSHN | PDPCSLNPHR | RSWAEKQCSI |
1100:
IKSDVFLACH | GKVDPTVFYD | ACVHDSCSCD | TGGDCECFCS | AVASYAQECT |
1150:
KAEACVFWRT | PDLCPVFCDY | YNPPDECEWH | YEPCGNRSFE | TCRTLNGIHS |
1200:
NISVSYLEGC | YPRCPEDRPI | YDEDLKKCVS | GDKCGCYIED | TRYPPGGSVP |
1250:
TDEICMSCTC | TNTSEIICRP | DEGKIINQTQ | DGIFCYWETC | GSNGTVEKHF |
1300:
EICVSSTLSP | TSMTSFTTTS | TPISTTPIST | TITTTSATAT | TTVPCCFWSD |
1350:
WINNNHPTSG | NGGDRENFEH | VCSAPENIEC | RAATDPKLDW | TELGQKVQCN |
1400:
VSEGLICNNE | DQYGTGQFEL | CYDYEIRVNC | CFPMEYCLST | VSPTTSTPIS |
1450:
STPQPTSSPT | TLPTTSPLTS | SATSPTTSHI | TSTVSPTTSP | TTSTTSPTTS |
1500:
PTTSTTSPTT | STTSPTPSPT | TSTTSPTPSP | TTSTTSPTPS | PTTSTTSPTT |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Chicken
Rat
Polyclonal Antibody for Rat MUC-2
Polyclonal Antibody for Rat MUC-2
Polyclonal Antibody for Rat MUC-2
Polyclonal Antibody for Rat MUC-2
Monoclonal Antibody for Rat MUC-2
Monoclonal Antibody for Rat MUC-2
Monoclonal Antibody for Rat MUC-2
Monoclonal Antibody for Rat MUC-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Intestine .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 21-36
tissue :
Intestinal epithelium .